Banner PFAS

Banner PFAS

Organic Chemistry Group (OC), Chemical Reference Laboratory Center (CRLC)

✨ 1. Significant Products:

Research analysis pertaining to organic compounds, encompassing both analytical methods for detecting various organic contaminants, naturally occurring substances, and emerging organic pollutants, as well as research focused on developing novel synthetic methodologies.

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🏢 2. Responsibilities of Group:

1. Research and develop organic chemistry testing standards in accordance with primary or secondary standards, or utilizing advanced techniques, to elevate the laboratory’s capabilities as a national reference center.
2. Research, develop, and analyze reference materials in organic chemistry for the benefit of laboratory development and quality control to ensure compliance with standards.
3. Conduct organic chemistry analyses as a nationally recognized reference laboratory to provide empirical evidence that products meet specified criteria, thereby complying with international regulatory standards.
4. Disseminate knowledge in chemical science and testing technology, provide academic consultation and advice, and offer research services to address various issues.
5. Establish and maintain a quality system in accordance with international standard ISO/IEC 17025 in organic chemistry to ensure highly accurate testing, serving as a model for other laboratories.
6. Support research and the development of scientific and technological standards in organic chemistry, and promote the capacity building of laboratories and the industrial sector to enhance testing and quality control capabilities.
7. Foster collaborative networks in academic and research and development dimensions with relevant national and international organizations.
8. Collaborate with relevant agencies in establishing product regulations and standards, both domestically and internationally.
9. Collaborate with or support the operations of other relevant agencies or as assigned by supervisors.

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🎯 3. Scope of Research Field:

Research analysis pertaining to organic compounds, encompassing both analytical methodologies for the detection of diverse organic contaminants, naturally occurring substances, and emerging organic pollutants, as well as research focused on developing novel synthetic approaches.

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🧪 4. Related Testing/Calibration:

• Per- and Polyfluoroalkyl substances (PFASs)
• Development of testing methods for Endocrine Disrupting Chemicals (EDCs)
• Accredited testing laboratory for detergents under Section 5 of the Industrial Product Standards Act, – performing tests in accordance with TIS 78-2549 Detergents.
• Chemical composition analysis of e-liquid (or vape juice)
• Analysis and testing of residual substances in recycled plastics (rPET)

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🥼 5. Testing Services:

• Per- and Polyfluoroalkyl substances (PFASs)
• Development of testing methods for Endocrine Disrupting Chemicals (EDCs)
• Accredited testing laboratory for detergents under Section 5 of the Industrial Product Standards Act, – performing tests in accordance with TIS 78-2549 Detergents.
• Chemical composition analysis of e-liquid (or vape juice)

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🔬 6. Key Scientific Instruments/Techniques:

• Gas Chromatography-Mass Spectrometry (GC-MS)
• Gas Chromatography with Flame Ionization Detector (GC-FID)
• Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
• High-Performance Liquid Chromatography with Diode Array Detector (HPLC-DAD)
• Fourier Transform Infrared Spectroscopy (FTIR)

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🏆 7. Outstanding Achievements/Awards and Honors:

–

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📄 8. Reference publications/Journal:

Uppalabat, T.; Tapdara, A.; Khaikate, O.; Worakul, T.; Surawatanawong, P.; Leowanawat, P.; Soorukram, D.; Reutrakul, V.; Meesin, J.; Kuhakarn, C. Synthesis of Indolo- and Benzothieno[3,2-c]quinolines via POCl3 Mediated Tandem Cyclization of o-Alkynylisocyanobenzenes Derived from o-Alkynyl-N-phenylformamides. New J. Chem. 2022, 46, 16333−16340.

Uppalabat, T.; Hassa, N.; Sawektreeratana, N.; Leowanawat, P.; Janthakit, P.; Nalaoh, P.; Promarak, V.; Soorukram, D.; Reutrakul, V.; Kuhakarn, C. Cascade Oxidative Trifluoromethylthiolation and Cyclization of 3-Alkyl-1-(2-(alkynyl)phenyl)indoles. J. Org. Chem. 2023, 88, 5403−5419.

Phetcharawetch, J.; Uppalabat, T.; Sawektreeratana, N.; Suwannapaporn, P.; Todsaporn, D.; Rungrotmongkol, T.; Muanprasat, C.; Kuhakarn, C. Identification of Sulfonylated Indolo[1,2-a]quinolines as EGFR Tyrosine Kinase Inhibitors. RSC Adv. 2025, 15, 3139−3146.

O. Apirakkan, C. Paimoolpiam, C. Peangpitak, N. Saesaengseerung, Assessing the quality of alcohol-based hand sanitizers purchased from Thailand’s online market using a GC-FID technique, Pure and Applied Chemistry International Conference 2024 (PACCON 2024), 2024.

O. Apirakkan, N. Saesaengseerung, O. Onjun, Estimation of total phenolic content and total carbonyl compounds for identifying natural rubber sheet smuggling into Thailand, World Chemistry Congress 2025 (WCC 2025), 2025.

Matos, W. O.; Sinaviwat, S.; da Silva, F. L. F.; Raab, A.; Krupp, E. M.; Feldmann, J. Fractionation and Spatial Distribution Analysis of Trace Elements in Wild and Farmed Shrimp from Northeast Brazil. Braz. J. Anal. Chem. (Forthcoming). http://dx.doi. org/10.30744/brjac.2179-3425.TN-169-2024 https://brjac.com.br/artigos/brjac-169-2024.pdf

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☎️ 9. Contact Persons: